This study found that individuals with the AG/GG genotype of the A118G SNP in the OPRM1 gene experienced more pleasant and fewer unpleasant effects from hydromorphone compared to those with the AA genotype, suggesting genotype-based differences in opioid sensitivity. Highlights: Positive Effects: Participants with the AG/GG genotype reported significantly more positive effects (e.g., good effects, …
Kratom is a plant gaining popularity as an alternative painkiller and recreational drug. But how much do we really know about its risks and benefits? About Kratom: Kratom is a tropical tree in the coffee family, native to Southeast Asia. People ingest its leaves to produce stimulant and opioid-like effects. Use is rising in the …
Xylazine is an animal tranquilizer increasingly being found in illicit drugs like heroin and fentanyl. This veterinary medication is not approved for human use but is linked to growing overdose deaths across the United States. Key Facts: Xylazine is a veterinary medication used to sedate large animals like horses and cattle. It is not approved …
