TL;DR: A 2026 medRxiv preprint found that a composite cerebral small vessel disease (cCSVD) score from routine T1 MRI predicted 3-month cognitive recovery after stroke better than any single small-vessel marker in a 65-person cohort. Key Findings Recovery window: The study analyzed 65 early subacute stroke survivors who completed baseline and 90-day follow-up visits. MRI …
TL;DR: A 2026 study in BMC Psychiatry found that structural MRI of the cerebellum separated first-episode bipolar depression from unipolar depression with 76.3% exploratory model accuracy, mainly because several cerebellar gray-matter regions were smaller in bipolar depression. Key Findings MRI cohort included three groups: Researchers analyzed structural MRI from 42 bipolar depression patients, 48 unipolar …
TL;DR: A 2026 MRI preprint on medRxiv found that patients with catatonia were less likely to have a left paracingulate sulcus (PCS), a stable anterior cingulate cortex fold, than psychiatric patients without catatonia. Key Findings 523 MRI scans: Researchers compared 109 patients with catatonia, 323 psychiatric patients without catatonia, and 91 healthy controls. Left PCS …
TL;DR: A 2026 study in Psychopharmacology found that healthy adults who used cannabis frequently had higher circulating THC markers after at least 12 hours of verified abstinence, but their cold-pressor pain threshold, pain tolerance, and pain ratings did not differ from occasional users. Key Findings 75 cannabis users were tested: the sample included 38 occasional …
TL;DR: A 2026 randomized trial in PLOS One found that one week of Bhagavad Gita learning, alone or paired with yoga, was associated with lower Generalized Anxiety Disorder-7 (GAD-7) scores in Indian healthcare workers, with the strongest 45-day responder rate in the Gita-only group. Key Findings 68 healthcare workers: Researchers randomized 17 participants each to …
TL;DR: A 2026 mouse and cell study in Signal Transduction and Targeted Therapy linked ATP11B, a phospholipid-flipping transport protein, to hippocampal iron handling, mitochondrial failure, ferroptosis, and age-related cognitive decline. Key Findings ATP11B fell with brain aging: Older mice showed lower blood-brain-barrier tight-junction markers and ATP11B emerged from integrated aging, endothelial-cell, and transport-gene analyses. ATP11B …
TL;DR: A 2026 BMC Psychiatry study found that antipsychotic dose was not associated with Montreal Cognitive Assessment (MoCA), a brief cognitive screening test, in clinically stable schizophrenia patients under 40, while higher symptom scores and longer illness duration tracked lower cognition. Key Findings Forty-one clinically stable outpatients with schizophrenia were included after researchers screened a …
TL;DR: A case study published in 2026 in BMC Neurology described a 45-year-old man with acute anti-glycine receptor progressive encephalomyelitis with rigidity and myoclonus (PERM), a stiff-person-spectrum disorder, whose sound-triggered muscle jerks repeatedly drove oxygen saturation down to 30% before immunotherapy and plasma exchange were followed by recovery. Key Findings Acute onset: Symptoms developed over …
TL;DR: A 2026 study in Scientific Reports found that 300 high-risk pregnant women in Egypt reported much lower pregnancy anxiety and stress scores after 4 weeks of daily AI chatbot emotional support, although the pre-post design cannot prove the chatbot caused the full change. Key Findings 300 high-risk pregnancies: Researchers recruited women aged 18-45 from …
TL;DR: A 2026 cross-sectional study in Scientific Reports found that attention-deficit/hyperactivity disorder (ADHD) symptom screening was linked to extremely severe chronic pain in 958 adults at Japanese pain centers, while autism spectrum disorder (ASD) screening was not clearly tied to pain intensity. Key Findings Referral pain sample: Researchers analyzed 958 adults with persistent chronic pain …
