TL;DR: At a leading London children’s hospital, 77 children with PRES, a sudden brain-swelling syndrome, were reviewed over 20 years. Nearly 4 in 5 first showed up with seizures, almost all had another serious illness, and about a third of those given seizure medicine still needed it after 6 months. Key Findings Seizures came first: …
TL;DR: Among older adults who walked on their own before breaking a hip, those with dementia or a low blood-based nutrition score a week after surgery were less likely to be walking independently when they left the hospital. The nutrition score alone was only a rough predictor. Key Findings Half lost independence: 88 of 173 …
TL;DR: In a German study of 34 people recovering from LGI1 encephalitis, a rare autoimmune brain disease, brain scans showed changes well beyond the memory centers usually blamed. People with more of these changes had poorer thinking scores and recovered less. Key Findings Most improved: Median disability score fell from 3 at the worst point …
TL;DR: In a phase III trial of 34 children with a rare inherited energy disorder, the drug dichloroacetate did not improve parent-rated movement problems more than placebo over 4 months. It did lower a harmful blood acid, lactate, and was well tolerated. Key Findings Main goal missed: Movement scores did not differ from placebo (p …
TL;DR: In a small Spanish trial, people with early Parkinson’s who did 12 weeks of strength training, with or without added thinking tasks, got faster on a walking test and stronger on a chair-stand test than people who did not exercise. Adding the thinking tasks gave no clear extra benefit. Key Findings 24 people, 3 …
TL;DR: People with a common type of heart failure scored lower on thinking tests than healthy people of similar age, and an MRI sign of the brain’s fluid-clearing system was lower on the left side of their brains. Lower values of that sign went with lower thinking scores. Key Findings Lower thinking scores: Average MoCA …
TL;DR: Teenage girls on a national youth soccer team who swapped two practices a week for weight training got stronger and did better on a classic focus test than teammates who kept their usual practice. Blood markers often linked to brain growth did not change. Key Findings 22 players, 12 weeks: Weight training plus soccer …
TL;DR: Among Hispanic and Latino adults in the U.S., people with one particular DNA pattern around the APOE gene were more likely to show steep thinking decline over about 7 years. The well-known APOE4 risk version had a weaker link in the same group. Key Findings 3 DNA profiles: Short DNA sequences near APOE sorted …
TL;DR: People recovering from stress-related exhaustion who did 12 weeks of computer brain training showed larger gains in thinking scores over 4.5 years than people who got rehab alone. Indoor cycling did not show the same lasting edge, but only 56 of 132 people came back. Key Findings Brain training held up: Bigger gains than …
TL;DR: When a piece of music ended differently than people expected, they were a bit more likely to remember pictures they saw around that moment a day later. The effect was small and showed up in trial-by-trial analyses, not in simple group averages. Key Findings 60 young adults: Listened to Bach chorales while viewing neutral …
