TL;DR: A 2026 study in Cureus found that a 55-year-old woman developed anxiety, somatic hypervigilance, and eventual delusional infestation after illicit cosmetic biopolymer injections, raising the possibility that chronic inflammatory exposure can help tip vulnerable patients into a secondary Ekbom syndrome. Key Findings One 55-year-old patient with no prior psychiatric history: The case centers on …
TL;DR: A 2026 study in Cognitive, Affective, & Behavioral Neuroscience found that visual working memory, the short-term holding of visual details, still showed a strong cardinal-versus-diagonal orientation bias under distraction, while transcranial direct current stimulation (tDCS), a weak noninvasive brain-stimulation method, did not improve task reports. Key Findings Two stimulation experiments tested orientation memory: Researchers …
TL;DR: A 2026 study in Journal of Sex Research found that in 571 German women, arousal to an aggressive written sexual narrative was better explained by sex drive, rape myth acceptance, and prior violent pornography exposure than by evolutionary life-history markers. Key Findings 571 women were quota-sampled: The German sample was selected to reflect age …
TL;DR: A 2026 study in Population Health Metrics used Global Burden of Disease 2019 estimates and found that U.S. substance-use-disorder health loss rose sharply from 1990 to 2019, with opioid use disorders driving the largest increase. Key Findings 19.5 million cases: Estimated U.S. substance use disorder prevalence increased from 12.6 million in 1990 to 19.5 …
TL;DR: A 2026 preprint cohort analysis in medRxiv found that about 24.1% of the sample met the PCL-5 threshold for probable post-traumatic stress disorder, or PTSD, while frequent uncensored video exposure was associated with higher PTSD symptom severity after accounting for other risk factors. Key Findings Indirect trauma design: Researchers studied people who were not …
TL;DR: A 2026 cohort study in The British Journal of Psychiatry found that lithium prescribing around pregnancy was rare in UK primary care records, and most pre-pregnancy lithium users did not stay on treatment through all three trimesters. Key Findings 752,112 pregnancies analyzed: Researchers used UK Clinical Practice Research Datalink GOLD records from 1995 to …
TL;DR: A 2025 study in Psychological Science found that depressive symptoms accelerated about 4 years before death in a multinational twin consortium, suggesting that late-life mood worsening can partly reflect terminal decline rather than chronological age alone. Key Findings 2,411 older-adult records: Researchers analyzed longitudinal depressive-symptom data from the Interplay of Genes and Environments across …
TL;DR: A 2026 fly study in IBRO Neuroscience Reports found that long-term rotenone exposure produced stronger survival, climbing, oxidative-stress, and late immune-gene disruption in male Drosophila than in female flies. Key Findings 90 flies per sex were tracked: Survival assays used three sets of 30 male or female flies after rotenone feeding. Two disease windows …
TL;DR: A 2026 systematic review in Molecular Psychiatry found that microglia-related findings across major depression, bipolar disorder, and schizophrenia were better explained by biological subgroups than by one uniform diagnosis-by-diagnosis inflammation pattern. Key Findings Three evidence streams: The review integrated human translocator protein positron emission tomography (TSPO-PET) imaging, cerebrospinal fluid kynurenine-pathway metabolites, and postmortem microglial …
TL;DR: A 2026 study in Psychiatry and Clinical Neurosciences Reports described a treatment-resistant residual-phase schizophrenia case in which valproate helped agitation but caused hypoglycemia and pancytopenia, while lithium augmentation was followed by lower hostility and excitement scores. Key Findings 49-year-old patient: The case involved a Japanese woman with chronic treatment-resistant schizophrenia and persistent agitation, aggression, …
