A Therapy App for Depression After Concussion Didn’t Beat an Education App

A Therapy App for Depression After Concussion Didn't Beat an Education App

TL;DR: A therapy app did not reduce depression scores more than a look-alike education app in a trial of adults with past concussions. Insomnia scores improved more with the therapy app, but only 42 of 113 participants completed the main 12-week check-in. Key Findings No edge on depression: Over 12 weeks, depression scores fell 2.0 …

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Repeated Brain Injuries From a Partner Linked to About a Decade of Extra ‘Cognitive Age’

Repeated Brain Injuries From a Partner Linked to About a Decade of Extra 'Cognitive Age'

TL;DR: Women who reported 10+ brain injuries from a partner performed on a speed test like someone about 21 years older than their actual age. They scored about 11 years “older” than survivors with no brain injury; the study of 207 women found a link, not proof that the injuries caused the difference. Key Findings …

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Lumateperone 42 mg Added to Antidepressants Increased Side Effects in Two Depression Trials

Lumateperone 42 mg Added to Antidepressants Increased Side Effects in Two Depression Trials

TL;DR: A 2026 pooled analysis in CNS Drugs combined two six-week trials of adults whose depression hadn’t responded well enough to an antidepressant. Adding the antipsychotic lumateperone instead of a placebo raised the share of people with side effects from 45.1% to 68.1% and the share who quit because of them from 0.8% to 8.7%. …

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Parkinson’s Disease Showed No Clear Difference in Creative-Thinking Scores Across 10 Studies

Parkinson's Disease Showed No Clear Difference in Creative-Thinking Scores Across 10 Studies

TL;DR: A 2026 meta-analysis in Neurological Sciences pooled 10 studies that gave people with Parkinson’s disease, tested while on their dopamine medication, and healthy adults the same “think of as many ideas as you can” tasks. On average, the two groups scored about the same, with neither a creative boost nor a clear deficit. Key …

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Cannabis Use Linked to About Double the Odds of Violence, With a Much Smaller Gap in Follow-Up Studies

Cannabis Use Linked to About Double the Odds of Violence, With a Much Smaller Gap in Follow-Up Studies

TL;DR: A meta-analysis pooling 63 studies and 265,079 people found that cannabis users had about twice the odds of committing violence as non-users (2.05 times in the general population, 2.49 times among psychiatric patients). The gap shrank to 1.17 times in studies that followed people over time. The design shows an association, not that cannabis …

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Mothers’ Depression Symptoms Tied to Toddler Sleep Problems, Mainly in Co-Sleeping Families

Mothers' Depression Symptoms Tied to Toddler Sleep Problems, Mainly in Co-Sleeping Families

TL;DR: In an online survey of 126 mothers of toddlers in Taiwan, mothers who reported more depressive symptoms also tended to describe their toddler’s sleep as more of a problem and to report longer times to fall asleep. The link with perceived sleep problems showed up in families where the toddler shared a sleeping surface …

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Dance Movement Therapy Linked to Lower Trauma, Stress, Depression and Anxiety Scores in 24 Refugee Women

Dance Movement Therapy Linked to Lower Trauma, Stress, Depression and Anxiety Scores in 24 Refugee Women

TL;DR: In a small German study of 24 refugee women with trauma symptoms, scores on three symptom questionnaires stayed flat during an 8-week wait, then dropped after 8 weekly dance movement therapy sessions. The group’s average PTSD checklist score slipped just under the usual clinical cutoff. There was no separate comparison group, so the study …

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Exercise in Pregnancy and After Birth Tied to Lower Depression Scores, With Low-Certainty Evidence

Exercise in Pregnancy and After Birth Tied to Lower Depression Scores, With Low-Certainty Evidence

TL;DR: A review of 17 randomized trials found that women who exercised had lower depression scores than women given usual care, both during pregnancy and after birth. The evidence is rated low to very low certainty, and the studies varied a lot. For anxiety during pregnancy, the review found no clear difference. Key Findings Depression …

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Two Weeks on an Ultra-Processed Diet Did Not Clearly Dull Fullness Signals in Healthy Adults

Two Weeks on an Ultra-Processed Diet Did Not Clearly Dull Fullness Signals in Healthy Adults

TL;DR: In a controlled Dutch feeding trial, 41 healthy young adults ate a diet made almost entirely of ultra-processed foods for two weeks, twice. Afterward, the gut hormones that help signal fullness responded to a test meal about the same as they had on the participants’ usual diets. Hunger and fullness ratings shifted only a …

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HEPA Air Purifiers Linked to Faster Thinking-Test Times in Adults 40 and Older, Not in Everyone

HEPA Air Purifiers Linked to Faster Thinking-Test Times in Adults 40 and Older, Not in Everyone

TL;DR: In a crossover trial of 119 adults living near busy highways, a month with a real HEPA air purifier did not clearly speed up a thinking test across the whole group. Among adults 40 and older, though, participants finished the harder test 12% faster after the real-purifier month than after the fake-purifier month. That …

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