Esports Gameplay Raised Physiology but Stayed Light Activity

Esports Gameplay Raised Physiology but Stayed Light Activity

TL;DR: A 2026 systematic review in Sports Medicine – Open found that esports gameplay can raise heart rate, stress physiology, and energy expenditure, but the overall metabolic demand generally stayed in the light-activity range. Key Findings 176 records screened: The review searched PubMed, Embase, SPORTDiscus, Web of Science, and Scopus before narrowing to 5 eligible …

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People With Dementia Supported AI Medication Reviews With Human Oversight

People With Dementia Supported AI Medication Reviews With Human Oversight

TL;DR: A 2026 preprint in medRxiv reported that people living with dementia (PLwD) and carers were generally open to artificial intelligence (AI) support in structured medication reviews, but only when AI remained validated, transparent, secure, and subordinate to human clinical judgement. Key Findings 26-person qualitative sample: Researchers interviewed 12 people living with dementia and ran …

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Watchful Waiting Left Symptoms in 57% of Children With Mild Sleep-Disordered Breathing

Watchful Waiting Left Symptoms in 57% of Children With Mild Sleep-Disordered Breathing

TL;DR: A 2026 study in Journal of Clinical Sleep Medicine found that after 12 months of watchful waiting for mild pediatric sleep-disordered breathing, only 13% of children progressed on polysomnography (PSG), an overnight sleep study, but 57% had persistent or worsening caregiver-reported symptoms. Key Findings 234 observed children: The analysis used the watchful-waiting arm of …

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Brain CT Was Normal in 72% of Acute Dizziness Emergency Cases

Brain CT Was Normal in 72% of Acute Dizziness Emergency Cases

TL;DR: A 2026 preprint in medRxiv found that routine non-contrast brain computed tomography (CT) had a low acute-pathology yield in 291 emergency patients with new dizziness, while diabetes, ataxic gait, and headache marked higher odds of abnormal CT findings. Key Findings 291-patient cohort: The retrospective analysis included consecutive adults with new-onset dizziness who underwent non-contrast …

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MBCT fMRI Manifolds Shifted During Rumination in Major Depression

MBCT fMRI Manifolds Shifted During Rumination in Major Depression

TL;DR: A 2026 medRxiv preprint used functional MRI (fMRI) and complex harmonics decomposition to study mindfulness-based cognitive therapy in 80 people with major depressive disorder, reporting post-treatment changes in whole-brain manifolds during rumination. Key Findings 80-patient trial sample: The preprint analyzed fMRI data from a randomized controlled trial in major depressive disorder. MBCT plus TAU: …

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EmulatRx Agentic AI Used Real-World Data for Clinical Trial Design

EmulatRx Agentic AI Used Real-World Data for Clinical Trial Design

TL;DR: A 2026 Nature Communications paper introduced EmulatRx, a multi-agent AI framework that used real-world clinical data to help design target-trial-emulation workflows for acute and chronic diseases, including Alzheimer disease and Parkinson disease examples. Key Findings 20-trial evaluation: Researchers curated 20 clinical trials, with 10 acute-condition trials from MIMIC-IV and 10 chronic-disease trials from INSIGHT. …

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Prenatal Active Smoking Linked to Higher Postpartum Depression Odds

Prenatal Active Smoking Linked to Higher Postpartum Depression Odds

TL;DR: A 2026 systematic review and meta-analysis in Archives of Women’s Mental Health linked prenatal active tobacco smoking with higher odds of postpartum depression, while secondhand smoke and electronic nicotine-product estimates were not statistically clear. Key Findings 29-study review: Researchers included 29 studies in the systematic review and 26 studies in the meta-analysis. 15% pooled …

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Transcriptomic Aging Was Accelerated in Major Depression and Linked to Right Insula Changes

Transcriptomic Aging Was Accelerated in Major Depression and Linked to Right Insula Changes

TL;DR: A 2026 case-control study in Psychological Medicine linked major depressive disorder to faster blood-based transcriptomic aging and found that right-insula brain changes partly explained the depression association. Key Findings Transcriptomic aging was faster in depression: 141 people with major depressive disorder showed higher blood RNA-based aging acceleration than 134 healthy controls. The result strengthened …

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Parent-Implemented Autism Intervention Helped Chinese Preschoolers

Parent-Implemented Autism Intervention Helped Chinese Preschoolers

TL;DR: A 2026 randomized trial in Molecular Autism found that a culturally adapted parent-implemented social communication program was linked to language, social-functioning, parent self-efficacy, and stress gains in Chinese-speaking autistic preschoolers, with no consistent advantage for therapist-led online groups over self-study across most outcomes. Key Findings Chinese preschoolers randomized: 112 autistic children aged 24-60 months …

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Refugee and Asylum Seeker Sleep Problems Were Common in Meta-Analysis

Refugee and Asylum Seeker Sleep Problems Were Common in Meta-Analysis

TL;DR: A 2026 meta-analysis in PLOS One found clinically important sleep problems in refugee and asylum-seeking populations, with pooled sleep-adversity prevalence of 43.2% in adults and 36.4% in children and adolescents. Key Findings 66 studies reviewed: The systematic review and meta-analysis covered 42,956 refugees and asylum seekers. 43.2% adult prevalence: Pooled sleep-adversity prevalence in adults …

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