EXPLORE THE SCIENCE
TL;DR: A 2026 mouse study in Translational Psychiatry reported that six days of adolescent THC exposure reduced Reelin-positive cell density in the female prefrontal cortex and cortical thickness across sexes. Prenatal immune activation did not consistently ma…
Read article
TL;DR: A 2026 medRxiv preprint linked greater attention-deficit/hyperactivity disorder (ADHD) symptom scores in college students to reduced stop-signal functional MRI (fMRI) activation in cannabinoid receptor 1 (CB1R)-rich brain regions, and that reduced activ…
Read article
TL;DR: A 2026 systematic review and meta-analysis in Molecular Psychiatry found that CB-1 receptor blockade and cannabidiol reduced alcohol intake in animal models, but human alcohol-use-disorder evidence remained inconsistent and too thin to support a treatme…
Read article
Cannabinoids Had Weak Evidence for Mental Disorders TL;DR: A Lancet Psychiatry review of randomized trials found little support for routine cannabinoid treatment in common mental disorders, despite possible weak signals in a few narrower conditions. Key Findin…
Read article
Cannabis Did Not Just Blur Word Lists. It Hit Everyday Memory Too TL;DR: A randomized vaporized-THC trial found broad acute memory impairment, including false memories, prospective memory, source memory, and temporal order memory, with no meaningful dose split…
Read article
Individuals at risk for cannabis use disorder (CUD) exhibit increased dynamic fluidity and altered connectivity patterns in brain networks, suggesting early changes in brain function that may contribute to cannabis addiction risk. Highlights: At-risk individua…
Read article
Cannabidiol (CBD) has recently emerged as a popular supplement among athletes looking to enhance recovery and performance. Key facts about CBD: CBD is a natural compound extracted from cannabis/hemp plants It does not cause psychoactive effects like THC CBD in…
Read article
A powerful, unregulated synthetic marijuana called “Tiburón” (Spanish for “shark”) has recently emerged in Honduras, posing severe risks to public health. Produced and sold by the notorious MS-13 street gang, this altered cannabis strain is designed to be even…
Read article
Cannabidiol (CBD) is emerging as a promising therapeutic for a variety of health conditions, but research is still in early stages. Here are some key facts on purified CBD: Purified CBD is showing positive results in clinical trials for anxiety, psychosis, sch…
Read article
Cannabis hyperemesis syndrome (CHS) is a newly recognized condition causing severe nausea and vomiting in long-term cannabis users. Key facts about CHS: Repeated, uncontrollable vomiting is the main symptom Occurs in long-term heavy cannabis users Exact cause…
Read article