Case Report: 10,000 mg Clozapine Overdose in 71-Year-Old Female (2024)

TLDR: This case study reports the highest recorded nonfatal clozapine overdose (10,000 mg) in an elderly patient, causing significant fluctuations in blood concentration levels following treatment. Highlights: A 71-year-old female ingested 10,000 mg of clozapine, significantly above typical overdose levels, leading to an initial blood concentration of 5200 μg/L. Despite initial treatment, blood clozapine levels …

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