TL;DR: A 2026 qualitative study in the Journal of Substance Use and Addiction Treatment found that syringe service programs helped people receive buprenorphine quickly, but participants said precipitated withdrawal and limited at-home initiation guidance made treatment harder to start and continue. Key Findings 12 exit interviews: Researchers interviewed people after a randomized trial of buprenorphine …
TL;DR: A 2026 systematic review and meta-analysis in Molecular Psychiatry found that CB-1 receptor blockade and cannabidiol reduced alcohol intake in animal models, but human alcohol-use-disorder evidence remained inconsistent and too thin to support a treatment claim. Key Findings 63 studies reviewed: Researchers synthesized 44 preclinical studies and 19 clinical or human experimental studies of …
TL;DR: A 2026 secondary analysis in Drug and Alcohol Dependence found 4 cannabis craving trajectories during treatment, with the high-craving group showing more positive urine cannabinoid tests and higher baseline anxiety, depression, and obsessive-compulsive cannabis-use symptoms. Key Findings Trial reanalysis: Researchers reanalyzed a 12-week multisite cannabis use disorder trial of 302 adults assigned to N-acetylcysteine …
People struggling with substance use disorders often have difficulties with memory, attention, planning, and decision-making. New research explores how these cognitive deficits relate to treatment outcomes and whether targeting them could improve addiction recovery. Key Facts: Cognitive deficits are common in people with substance use disorders, especially relating to memory, attention, self-control, and reward-based decision-making. …
Prescription opioid painkillers like oxycodone can be very addictive. People who use them for a long time often have trouble stopping, even if the drugs start causing problems. A new study tested a drug that blocks brain signals that keep people wanting opioids. The drug helped rats stop seeking oxycodone and improved their sleep and …
