MGAT5B Loss Broadened Nodes of Ranvier and Delayed Axonal Conduction in Mice
TL;DR: A 2026 mouse study in Communications Biology found that loss of MGAT5B, a brain-enriched enzyme that branches O-mannose sugars on proteins, widened nodes of Ranvier—the intervals between myelin segments that organize axon signaling—and delayed callosal…
Read article