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Neuropsychiatric DisordersJune 23, 2026

Stress Disrupted Social Behavior Through mPFC Oxytocin Circuit

TL;DR: A 2026 study in Communications Biology found that restraint stress weakened medial prefrontal cortex (mPFC, a frontal brain region that helps organize social behavior) activity during social testing, while stress-activated amygdala and hypothalamic oxyt…

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Neuropsychiatric DisordersOctober 7, 2023

Borderline & Avoidant Personality Disorders: Brain Structure Abnormalities & Neurobiology

Personality disorders like borderline and avoidant involve differences in brain structure and function that relate to symptoms. New research sheds light on the neurobiology underlying these disorders. Key Facts: Borderline patients showed reduced medial prefro…

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Stress Disrupted Social Behavior Through mPFC Oxytocin Circuit

Borderline & Avoidant Personality Disorders: Brain Structure Abnormalities & Neurobiology

The findings. The context. The caveats.