Cocaine abuse leads to dysfunction of brain dopamine systems and the development of addiction. New research identifies changes in the dopamine transporter as a driving force underlying cocaine addiction, and points to a novel way to reverse these detrimental effects. Key Facts: Cocaine abuse caused the dopamine transporter to form larger complexes of multiple transporter …
A series of studies suggest that repeated low doses of d-amphetamine can lead to a progressively greater behavioral response in some people. This phenomenon, known as “behavioral sensitization,” has been observed in animal models and hypothesized to contribute to addiction in humans. However, few controlled human studies have directly tested this idea. A new double-blind, …
Modafinil is a prescription medication often used off-label as a ‘smart drug’ to boost focus and concentration. While thought to have low potential for abuse, emerging case reports reveal that modafinil may be more addictive than previously believed. What is Modafinil? Modafinil is a prescription medication approved for treating sleep disorders like narcolepsy, shift work …
