Bipolar Mania & Brain Activation: Right Ventral PFC & Limbic Dysfunction
Mania is characterized by emotional dysregulation, sleep disturbances, and impaired judgment. Understanding its underlying brain circuitry could lead to improved diagnosis and treatment. Key Facts: Mania involves decreased activity in the right ventral prefrontal cortex (PFC) and increased activity in the left amygdala, left anterior cingulate cortex (ACC), and left basal ganglia. This lateralized limbic …
