Semaglutide Reduces Alcohol Drinking in Mice: Potential Addiction Treatment

The FDA-approved diabetes drug semaglutide reduces alcohol drinking in mice and rats, suggesting it could be repurposed as an effective medication for alcohol use disorder (AUD). Key findings include: Semaglutide dose-dependently decreased binge-like drinking in both male and female mice. In rats, semaglutide reduced binge-like and dependence-induced alcohol drinking. Semaglutide also decreased consumption of caloric …

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MDMA Assisted Therapy for Alcohol Abuse & PTSD

A new study provides preliminary evidence that MDMA-assisted therapy may help reduce alcohol use in people with severe PTSD. Key facts: MDMA-assisted therapy was tested in a phase 3 clinical trial for treating severe PTSD. Participants were allowed to have mild alcohol or cannabis use disorder. Compared to placebo therapy, MDMA therapy led to greater …

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