Cocaine Addiction Linked to Brain Shrinkage & Grey Matter Deficits (2024 Study)

Cocaine Use Disorder (CUD) patients exhibit widespread gray matter atrophy, with specific brain volume deficits associated with crack-cocaine use and relapse outcomes. Highlights: Widespread Gray Matter Atrophy: CUD patients show significant gray matter volume reductions in frontal and temporal cortices, cerebellum, and subcortical structures compared to healthy controls. Route of Use: Crack-cocaine use is linked …

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Intranasal Insulin for Mild Cognitive Impairment: Enhancing Social Skills, Memory, Grey Matter Volume (2024 Case Report)

Extended intra-nasal insulin (INI) treatment in an insulin-resistant early Mild Cognitive Impairment (MCI) patient improved grey matter volume, reduced beta-amyloid levels, and enhanced cognitive and pragmatic capacities, suggesting potential to slow neurodegenerative disease progression. Highlights: Grey Matter Volume: After 9 months of INI treatment, the patient experienced an increase in grey matter volume. Beta-Amyloid Levels: …

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