Estradiol for Cognitive Enhancement: Hormone Replacement Therapy (HRT) Research
Estradiol enhances memory and other aspects of cognition in animals and humans, but translating the research into effective hormone replacement therapies (HRTs) has faced challenges. Recent developments indicate multiple mechanisms, along with some key facts: Estradiol enhances memory consolidation via genomic and rapid signaling cascades acting minutes-to-hours after learning. Synaptic plasticity and spine remodeling appear …
