Psilocybin AUD Trial Found Exploratory TLE4 and RASGRP4 Methylation Signals
TL;DR: A 2026 exploratory study in Translational Psychiatry found blood DNA methylation changes after 25 mg psilocybin in detoxified alcohol use disorder patients, including findings near TLE4 and RASGRP4, but the small trial did not establish a definitive AUD biomarker. Key Findings 37 AUD patients: The methylation analysis used a randomized, double-blind psilocybin trial completed …
