NLRP3 Inflammasome & Depression: Antidepressant Potential with Targeted Therapy?
The NLRP3 inflammasome is increasingly being recognized as a mediator between inflammation and depression. Targeting this molecular complex shows promise for developing new antidepressant therapies. Key Facts: The NLRP3 inflammasome is made up of NLRP3, ASC, and caspase-1 proteins that trigger inflammatory responses when activated. Evidence shows the NLRP3 inflammasome is overactivated in the brains …
