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DepressionOctober 2, 2026

Trazodone May Boost Deep Sleep in Depression, but Causes Drowsiness

TL;DR: In a pooled review of 8 studies of 980 people with depression and sleep problems, sleep tests showed more deep sleep and less light sleep after taking trazodone than before. Compared with placebo, though, the deep-sleep gain was not clear, and drowsines…

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AntidepressantsDecember 28, 2023

Antidepressants for Insomnia Treatment in Adults: Are They Effective? (Cochrane Review Findings)

Insomnia is a common sleep disorder affecting up to 15% of adults. While sedative medications are often prescribed, their long-term use can lead to dependence. As an alternative, antidepressants are widely used in clinical practice despite limited evidence sup…

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Trazodone May Boost Deep Sleep in Depression, but Causes Drowsiness

Antidepressants for Insomnia Treatment in Adults: Are They Effective? (Cochrane Review Findings)

The findings. The context. The caveats.