Antidepressants & Mania Risk in Bipolar Patients via Mitochondrial Effects
A new Mayo Clinic study is the first to clinically investigate whether antidepressants that impact mitochondrial function differently are associated with varying rates of treatment-emergent mania in bipolar disorder. The study found that antidepressants that increase mitochondrial energetics were associated with nearly double the rates of treatment-emergent mania compared to antidepressants that decrease mitochondrial energetics. …
