tricyclic antidepressants

Antidepressants for Insomnia Treatment in Adults: Are They Effective? (Cochrane Review Findings)

by

Insomnia is a common sleep disorder affecting up to 15% of adults. While sedative medications are often prescribed, their long-term use can lead to dependence. As an alternative, antidepressants are widely used in clinical practice despite limited evidence supporting their efficacy and safety for insomnia. Key Facts: Insomnia affects up to 15% of adults, causing …

Read more

Antidepressants for Cancer Treatment via Autophagy Modulation?

by

Antidepressants could potentially be repurposed as anticancer agents based on emerging evidence showing they can modulate autophagy—a process cancer cells rely on for growth and survival. Key Facts: Many antidepressants like SSRIs and TCAs have demonstrated anticancer effects in lab studies. Their mechanisms involve regulating autophagy, which plays a complex role in cancer development. Specific …

Read more