How Nitric Oxide Damages TSC2 to Drive Autism Behaviors via mTOR
Nitric Oxide’s Hidden Link to Autism Behavior TL;DR: A chemical messenger called nitric oxide triggers protein damage that sends the mTOR pathway into overdrive in autism-related mouse models, driving social deficits and repetitive behaviors—and blocking this mechanism reverses both the molecular dysfunction and autistic-like behaviors. Autism spectrum disorder involves dozens of genetic variants, yet many …
