EXPLORE THE SCIENCE
TL;DR: A 2026 Nature Communications study found that small sets of amino-acid changes could swap ligand preference between beta2 adrenergic and D1 dopamine receptors, showing that receptor selectivity depends on both the binding pocket and surrounding structur…
Read article
Alcohol use disorder (AUD) is associated with impairments in dopamine (DA) neurotransmission, with significant differences in DA release, receptor availability, and transporter density observed across different levels of alcohol consumption and stages of AUD.…
Read article
Researchers have uncovered new insights into how fasting alters dopamine signaling in the brain’s reward circuitry. Their findings, published in the Journal of Neurophysiology, suggest that fasted mice exhibit enhanced dopamine release in the ventral tegmental…
Read article
Amphetamine is well known for its ability to increase dopamine levels in the brain. But new research suggests the psychostimulant drug may also directly alter dopamine 2 receptors, with implications for behavioral effects and physiological changes seen after c…
Read article