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TL;DR: A 2026 mouse study in Neurochemical Research found that 28 days of unpredictable chronic mild stress increased dopamine D1 receptor binding across the striatum and raised dopamine D2 receptor binding only in selected regions, regardless of fatty acid-bi…
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TL;DR: A 2026 mouse preprint in bioRxiv found that psilocybin reduced firing in somatostatin (SST) interneurons, inhibitory cortical cells that gate dendritic input, while increasing parvalbumin (PV) interneuron firing in the medial frontal cortex. Key Finding…
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Allopregnanolone shows antidepressant-like effects in mice by increasing social interaction and specific brain wave activities, unlike diazepam. Highlights: Allopregnanolone: Allopregnanolone, a neuroactive steroid, increases social interaction time in mice ex…
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