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Nature Methods

Brain Computer InterfacesJune 29, 2026

Neuropixels Opto Combined Electrophysiology and Optogenetics

TL;DR: A 2026 methods paper in Nature Methods describes Neuropixels Opto probes that combine high-density neural recording with spatially addressable blue and red optogenetic stimulation in 1 mouse-brain device. Key Findings 960 recording sites: Each prototype…

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Artificial Intelligence (AI)June 5, 2026

Self-Localized Pencil Beam Improved 3D Multiphoton BBB Imaging

TL;DR: A 2026 Nature Methods paper described a self-localized ultrafast pencil beam that made volumetric multiphoton imaging faster and more stable, including 1-minute 3D scans of transferrin uptake in a live human blood-brain barrier model. Key Findings Optic…

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Neuropixels Opto Combined Electrophysiology and Optogenetics

Self-Localized Pencil Beam Improved 3D Multiphoton BBB Imaging

The findings. The context. The caveats.