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phagocytosis

Genetics & EpigeneticsJune 4, 2026

Microglia CRISPR Screen Linked Schizophrenia Genes to Phagocytosis

TL;DR: A 2026 study in Neuropsychopharmacology used CRISPR gene editing in human microglia-like cells and found that several schizophrenia-linked genes changed phagocytosis, cell shape, and immune-transcription programs. Key Findings Schizophrenia-linked micro…

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AlzheimersApril 20, 2026

How Lecanemab Clears Amyloid: The Microglia & SPP1 Mechanism

How Lecanemab Clears Brain Amyloid: The Microglia Key TL;DR: Lecanemab, the first Alzheimer’s antibody to slow cognitive decline, works by activating immune cells called microglia through a specific immune signaling pathway, with the molecule SPP1/osteopontin…

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Microglia CRISPR Screen Linked Schizophrenia Genes to Phagocytosis

How Lecanemab Clears Amyloid: The Microglia & SPP1 Mechanism

The findings. The context. The caveats.