Caudal Insular-to-Somatosensory Pathway Was Necessary and Sufficient for Neuropathic Pain in Rats
TL;DR: A 2025 rat study in The Journal of Neuroscience found that caudal granular insular cortex (CGIC) projections to primary somatosensory cortex (SI) were required for neuropathic pain behavior, while activating the same pathway produced allodynia, or pain…
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