Intranasal Oxytocin May Effectively Treat a Subtype of Autism in Children

A recent study identified that young autistic children with lower clinical severity and greater eye contact are more likely to respond positively to intranasal oxytocin treatment. Highlights: Response Rate: 61.5% of one identified autism subtype responded to oxytocin, compared to only 13.3% of the other subtype. Predictive Measures: Baseline measures of lower initial clinical severity …

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Predicting Responders to Minocycline for Depression via Clinical Subgroups

Major depressive disorder (MDD) is a highly prevalent mental illness and leading cause of disability worldwide. While treatments exist, they are far from optimal and up to 30% of patients fail to respond. There is an urgent need to identify factors that may enhance treatment response in MDD. Targeting inflammation has been proposed as a …

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