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TL;DR: A 2026 study in Neuropsychopharmacology Reports found that repeated cigarette smoking and quitting shifted clozapine metabolism in one Japanese man with treatment-resistant schizophrenia, with the dose-adjusted clozapine level falling during smoking per…
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TL;DR: A 2026 study protocol in Trials describes COSTS, a randomized trial that will compare cognitive behavioral therapy for insomnia (CBT-I) with standard cognitive behavioral therapy (CBT) in 60 people with treatment-resistant schizophrenia and persistent s…
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TL;DR: A 2026 case study in Psychiatry and Clinical Neurosciences Reports described a 36-year-old man with treatment-resistant schizophrenia and focal epilepsy whose psychosis improved after slow clozapine titration, without worsening seizure frequency or seve…
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TL;DR: A 2026 preprint in medRxiv trained machine-learning models on Danish electronic health records and found that an XGBoost model predicted clozapine initiation within 365 days with an AUROC of 0.81 in patients with schizophrenia or schizoaffective disorde…
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