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Major depressive disorder affects over 17 million American adults each year. For up to 30% of these patients, standard antidepressant medications fail to provide adequate symptom relief – a condition known as treatment-resistant depression (TRD). Now, new rese…
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Vagus nerve stimulation (VNS) is an emerging form of brain stimulation showing promise for treating depression. Though still considered experimental, VNS has a long history dating back over 100 years. Recent advances are unlocking its potential as a new tool f…
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Historically, cuckoldry rates have been remarkably low in many societies around the world. Though popular belief holds that 10-30% of children are the product of female infidelity, recent genetic research shows the rate is actually around 1-2%. This challenges…
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Suicide is a major public health problem, with over 700,000 people dying by suicide every year globally. Identifying factors that may indicate risk for suicidal thoughts and behaviors is an important area of research, as this could aid prevention and intervent…
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Transcranial magnetic stimulation (TMS) is showing promise as a non-invasive treatment approach for tinnitus in some patients. Research indicates it may be able to reduce tinnitus loudness and annoyance by modulating brain activity. However, significant questi…
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Sexual sharing paraphilias like cuckolding and troilism have long been taboo yet widespread practices. New clinical research sheds light on the pathological roots of these unconventional behaviors. Key Facts: Study finds traumatic experiences in youth trigger…
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Bipolar disorder, formerly known as manic depression, is a chronic mental illness characterized by dramatic shifts in mood and energy levels. It affects about 2-4% of the population worldwide. While we still don’t fully understand what causes bipolar disorder,…
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Mania is characterized by emotional dysregulation, sleep disturbances, and impaired judgment. Understanding its underlying brain circuitry could lead to improved diagnosis and treatment. Key Facts: Mania involves decreased activity in the right ventral prefron…
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Deep brain stimulation (DBS) is an effective but not perfect therapy. A large new study found that over 4-7 years, a majority of patients experienced adverse events, though most were not severe. Key facts: 86% of 123 DBS patients experienced adverse events ove…
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L-carnitine is a naturally occurring compound that plays a key role in energy production in the body. Some research suggests it may enhance cognitive function, but does it really work as a nootropic or “smart drug” in healthy people? Key Facts: L-carnitine is…
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