Cognition

Selegiline Reverses Anxiety & Memory Impairment in Amyloid Beta-Induced Alzheimers Model Rats (2024 Study)

by

The study demonstrated that selegiline (SEL) improves memory performance, reduces anxiety, and modulates oxidative stress in an Alzheimer’s disease (AD) rat model. Highlights: Memory Improvements: SEL administration improved recognition memory, spatial memory, and passive avoidance memory in AD rats. Anxiety Reduction: SEL significantly reduced anxiety-like behavior in AD rats, as evidenced by performance in the …

Read more

Intranasal Insulin for Mild Cognitive Impairment: Enhancing Social Skills, Memory, Grey Matter Volume (2024 Case Report)

by

Extended intra-nasal insulin (INI) treatment in an insulin-resistant early Mild Cognitive Impairment (MCI) patient improved grey matter volume, reduced beta-amyloid levels, and enhanced cognitive and pragmatic capacities, suggesting potential to slow neurodegenerative disease progression. Highlights: Grey Matter Volume: After 9 months of INI treatment, the patient experienced an increase in grey matter volume. Beta-Amyloid Levels: …

Read more

Hypertension Linked to Impaired Cognition & Gait in Older Adults (2024 Study)

by

Hypertension in older adults leads to poorer cognitive and walking performance due to the need for more brain resources to manage dual tasks. Highlights: Older adults with hypertension show higher brain activation in motor and sensory areas when performing dual cognitive-walking tasks compared to healthy peers. Hypertensive individuals have worse cognitive performance on single cognitive …

Read more

Age-Related Brain Volume Changes in Men & Women (2024 MRI Study)

by

Normal aging leads to a decrease in brain volume, with gray and white matter shrinking and cerebrospinal fluid increasing, as measured by synthetic MRI. Highlights: Study Sample: 300 healthy adults (141 males, median age 48; 159 females, median age 50) were analyzed using synthetic MRI. Brain Volume Trends: Brain parenchymal volume (nBPV) decreases steadily with …

Read more

Aesthetic Chills (Frisson) May Help Treat Depression: Goosebumps from Emotional Stimuli (2024 Study)

by

Experiencing aesthetic chills can positively influence self-related beliefs in people with depression, similar to the effects of psychedelics, suggesting potential as a non-pharmacological intervention. Highlights: Novel Approach: Aesthetic chills, characterized by physical sensations like shivers and goosebumps, may help shift negative cognitive patterns in depression. Study Results: 96 patients with major depressive disorder showed positive …

Read more

Effects of Water Pollution on the Brain & Strategies to Avoid Neurotoxicity (2024)

by

Water pollution poses serious risks to human brain health, leading to neurological damage and increased risk of neuropsychiatric diseases. Highlights: Sources of Pollution: Water sources are contaminated by industrial waste, agricultural runoff, and urban waste, introducing harmful chemicals like pesticides, inorganic salts, and organic compounds into drinking water. Neurological Impact: Chemicals such as acrylamide in …

Read more

1-Year Post-COVID Neuropsychiatric Symptoms: Fatigue, Cognition, Anxiety, Depression, Headache, Dizziness (2024 Study)

by

A study found that adults recovering from their first COVID-19 infection more than 1-year ago have higher levels of fatigue and other chronic neuropsychiatric symptoms, influenced by vaccination status and socioeconomic factors. Highlights: Adults who had their first COVID-19 infection over 1-year ago reported significantly higher fatigue levels compared to those who never had COVID-19 …

Read more

Chess Experts Differ in Chunk Memory & Brain Connectivity vs. Novices (2024 Study)

by

Expert chess players use chunk memory to make better decisions, showing unique brain connectivity that helps them perform well even against tougher opponents. Highlights: Consistent Performance: Expert chess players perform equally well regardless of the difficulty level, unlike beginners whose performance drops with increased difficulty. Stronger Brain Connections: Experts show stronger connections in specific brain …

Read more

Peptide PHDP5 May Reverse Cognitive Impairment in Alzheimers Disease (2024 Research)

by

TLDR: Researchers demonstrated that intranasal administration of the peptide FITC-PHDP5-CPP reverses early cognitive impairment in Alzheimer’s disease (AD) model mice, showing potential as a treatment for AD-associated cognitive decline. Highlights: PHDP5, derived from the pleckstrin homology domain of dynamin 1, inhibits the interaction between dynamin and microtubules, rescuing synaptic dysfunction caused by tau accumulation. The …

Read more

+ Load more