Cognition

Psychedelics Double 5-Hz Brain Oscillations in Visual Cortex to Produce Hallucinations

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How Psychedelics Hijack Brain Waves to Create Hallucinations TL;DR: A psychedelic drug that activates serotonin receptors dramatically amplifies slow 5-Hz brain oscillations in visual and memory regions, suggesting a mechanism for how hallucinogens distort perception by letting internal signals override external reality. Visual perception feels stable, seamless, continuous. But that stability is an illusion orchestrated …

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New Blood Test Detects Alzheimer’s Disease with 83% Accuracy Years Before Symptoms

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Blood Test Detects Alzheimer’s with 83% Accuracy TL;DR: A new blood test using three misfolded plasma proteins can identify Alzheimer’s disease with 83.44% accuracy, outperforming conventional biomarkers and offering a non-invasive screening tool years before cognitive symptoms appear. The holy grail of Alzheimer’s research isn’t a cure—yet. It’s catching the disease before memory starts to …

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Video Game Addiction vs. Brain Activity & Response Inhibition: A Cued Go/NoGo Task Study

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Video game addiction (VGA) is associated with significant deficits in response inhibition and preparatory processes, reflected by more commission errors and reduced N2 amplitudes in the cued Go/NoGo task. Highlights: Increased Commission Errors: Individuals with VGA made significantly more commission errors in NoGo trials compared to healthy controls, indicating impaired response inhibition. Faster Reaction Times: …

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Omega-3 Fatty Acids & Souvenaid® May Slow Cognitive Decline in Alzheimer’s Disease (2024 Review)

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Omega-3 supplements and Souvenaid® show potential in slowing cognitive decline in Alzheimer’s patients, though the evidence remains inconclusive. Highlights: Cognitive Decline Reduction: The CDR scale showed a significant reduction in cognitive decline progression with Omega-3 supplementation (SMD = −0.4127, 95% CI: [−0.5926; −0.2327]). Mixed Cognitive Outcomes: 58% of studies reported positive cognitive effects from Omega-3 …

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Guanfacine Reverses Cognitive Impairment in Long COVID (2024 Case Report)

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Guanfacine extended release (GXR) may effectively improve cognitive impairments and brain activity in long-COVID patients. Highlights: Patient Presentation: A 32-year-old woman experienced cognitive impairments such as difficulty in word recall, reading, and writing, and delayed task completion following COVID-19 infection. Baseline Assessment: Initial tests showed poor performance in attention, working memory, and executive function, with …

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ACOT7 Biomarker May Help in Early Diagnosis of Alzheimers Disease (2024 Study)

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ACOT7 shows promise as a non-invasive serum biomarker for Alzheimer’s disease (AD) with high diagnostic accuracy. Highlights: Increased Expression: ACOT7 levels were significantly elevated in AD patients and animal models compared to controls. Correlation with Cognitive Decline: A strong negative correlation was observed between serum ACOT7 levels and MMSE scores (r = -0.85; p < …

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Blood Urea Nitrogen (BUN) & Creatinine Ratio vs. Cognition & Depression (2024 Study)

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Elevated blood urea nitrogen and creatinine ratio (BUNCr) is associated with decreased cognitive function and increased depressive symptoms, with depressive symptoms mediating part of the relationship between BUNCr and cognitive decline. Highlights: BUNCr has a negative association with cognitive function, with higher BUNCr levels linked to lower cognitive performance. BUNCr is positively associated with depressive …

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High Stress in Midlife Linked to Dementia in Women (2024 Study)

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Women experiencing midlife stress-related exhaustion have a higher risk of developing dementia at a younger age and exhibit long-term cognitive impairments. Highlights: Higher Dementia Risk: Women with midlife stress-related exhaustion had a nearly threefold increased risk of developing dementia before age 75. Earlier Onset: The average age of dementia onset was younger for women with …

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White & Black Americans Exhibit Differences in Brain Structure, Volume, Cortical Thickness (2023 Study)

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This study reveals significant differences in brain morphology between neurotypical young adults identified as White or African American, highlighting the impact of racial identity on brain structure. Highlights: Brain Volume Differences: Significant volumetric differences were found in white matter, subcortical regions, and the choroid plexus between White and African American participants. Cortical Thickness Variability: Differences …

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Fidgeting May Enhance Attention in Adults with ADHD During Cognitively Demanding Tasks (2024 Study)

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Fidgeting in adults with ADHD may serve as a compensatory mechanism to sustain attention during cognitively demanding tasks, particularly during correct task performance and when reaction time variability is low. Highlights: Fidgeting was significantly higher during correct trials compared to incorrect trials, suggesting it may aid in task performance. Increased fidgeting was observed in later …

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