Researchers have discovered that classic psychedelic drugs like LSD and psilocybin (‘magic mushrooms’) flatten the energy landscape of the brain. This effect makes it easier for the brain to transition between different states of activity and leads to more diverse and entropic neural dynamics overall. Key Facts: Using fMRI data and network modeling, researchers found …
Major depressive disorder affects over 280 million people worldwide. While the causes are complex, new research is uncovering the role epigenetics plays in depression. Epigenetic changes can regulate how genes are expressed without altering the DNA sequence itself. These changes may explain why some people are more susceptible to depression and highlight new avenues for …
A new brain imaging study provides insight into how antidepressants like selective serotonin reuptake inhibitors (SSRIs) may bring about symptom improvement in adolescents with major depressive disorder. The findings suggest that changes in a brain region involved in cognitive control may serve as markers of treatment response. Key Facts: Researchers used MRI scans to examine …
A new study reveals that widely prescribed antidepressants may cause persistent erectile dysfunction in a small but significant number of male patients. Key Facts: The study found that serotonergic antidepressants like SSRIs and SNRIs triple the risk of erectile dysfunction (ED) compared to non-users. After stopping the antidepressants, 0.46% of patients (1 out of every …
Researchers have found signs of ongoing inflammation in the brains of athletes still experiencing concussion symptoms months or years after their injury, according to a new study published in Journal of Neuroinflammation. The findings suggest the concussion triggered chronic neuroinflammation that may be contributing to their persistent symptoms. Key Facts: The study examined athletes who …
Cannabis legalization is spreading, but what does it mean for public health? A new review summarizes the research on the impacts of legalizing recreational cannabis use. Key Facts: Recreational cannabis is now legal nationally in Canada, Uruguay, and Malta. 18 U.S. states plus D.C. have also legalized recreational use. Research finds mixed evidence for effects …
Summary: A new study published in Environmental Health Perspectives found that people who exclusively use marijuana have higher levels of toxic metals like cadmium and lead in their blood and urine compared to people who do not use marijuana or tobacco. Key Facts: Exclusive marijuana users had 22% higher blood cadmium levels and 27% higher …
A study finds that antidepressant treatment reduces empathy – but depression itself doesn’t impact empathy. Key Facts: People with untreated depression showed normal empathy and brain responses. After 3 months of antidepressant treatment, they showed reduced empathy and brain responses. The more their depressive symptoms improved, the more their empathy decreased. Antidepressants specifically reduced emotional …
