Transcranial Direct Current Stimulation (tDCS) of Left Dorsolateral Prefrontal Cortex Seems Effective for Depression & Anxiety (2024 Review)

Transcranial direct current stimulation (tDCS) targeting the left dorsolateral prefrontal cortex (DLPFC) at 2-mA intensity effectively alleviates depressive symptoms and shows promise in reducing anxiety symptoms across various clinical conditions. Highlights: tDCS targeting the left DLPFC significantly reduces depressive symptoms, highlighting it as a transdiagnostic neural mechanism across diverse clinical conditions. The meta-analysis showed that …

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rTMS of Left Dorsolateral Prefrontal Cortex (DL-PFC) May Treat Methamphetamine Addiction via Altering Cravings & Decision Making (2024 Study)

Repetitive transcranial magnetic stimulation (rTMS) on the left dorsolateral prefrontal cortex (dlPFC) improves decision-making and reduces cravings in individuals with methamphetamine use disorder (MUD). Highlights: Improved Decision-Making: rTMS treatment enhanced decision-making abilities in MUD patients, making their choices more rational and similar to healthy individuals. Craving Reduction: Participants experienced a significant decrease in cravings for …

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TMS is Effective But Underutilized for Major Depression vs. Standard of Care (2024 Study)

Transcranial magnetic stimulation (TMS) is underutilized in treating major depressive disorder (MDD) despite showing significant clinical benefits, with barriers including insurance coverage and limited access. Highlights: Study Scope: Analyzed real-world data from a large, multi-site psychiatric practice to evaluate TMS utilization and outcomes compared to usual care (UC) for patients with MDD. Patient Cohorts: Among …

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Transcranial Alternating Current Stimulation (TACS) for Depression: Effective Adjunct via Reducing Prefrontal Alpha Waves (2024 Trial)

Adding transcranial alternating current stimulation (tACS) to antidepressant treatment improves depression symptoms more effectively than using antidepressants alone. Highlights: Enhanced Efficacy: tACS combined with antidepressants significantly reduces depression symptoms compared to antidepressant treatment alone. Lasting Effects: The additional antidepressant benefits of tACS persist for at least 4 weeks after treatment ends. Brain Activity Changes: Patients …

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rTMS Improves Blood Biomarkers (BDNF, GDNF, Thiol, S100B) in Depression (2024 Study)

Repetitive transcranial magnetic stimulation (rTMS) therapy improves key biochemical markers in major depressive disorder (MDD) patients, indicating its effectiveness as an antidepressant treatment. Highlights: Improved Antioxidant Levels: rTMS therapy significantly increased total antioxidant status (TAS), total thiol (TT), and native thiol (NT) levels in MDD patients compared to their levels before treatment. Reduced Oxidative Stress: …

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Alpha Closed-Loop Auditory Stimulation Increases Alpha Brain Waves & Alters Sleep (2024 Study)

TLDR: A new method using sound to influence brain waves can help manage brain activity and affect how we fall asleep. Highlights: How It Works: This method, called Alpha Closed-Loop Auditory Stimulation (αCLAS), uses sound pulses timed precisely to brain waves to change brain activity. Phase Matters: The timing of the sound pulses is crucial; …

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Transcranial Magnetic Stimulation (TMS) for Cognitive Enhancement: What the Research Suggests

Transcranial Magnetic Stimulation (TMS) is emerging as a revolutionary tool in enhancing cognitive functions, with over sixty studies indicating significant improvements in various tasks. Unlike traditional pharmaceutical approaches, TMS offers a non-invasive alternative to modulate brain activity, potentially benefiting healthy individuals and those with neurological conditions. Key Facts: Over 60 Studies Show TMS Enhancement: Research …

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Neurofeedback for Cognitive Enhancement & Neuroplasticity?

Neurofeedback is a promising technique that allows people to voluntarily control their own brain activity with the goal of improving cognitive functions or relieving symptoms. Key Facts: Neurofeedback provides real-time feedback on brain activity, allowing a person to learn to control activity in specific brain regions. It has shown clinical benefits for disorders like ADHD, …

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Continuous Theta Burst Stimulation (cTBS) Ineffective for Depression? (New Meta-Analysis Reports No Benefit)

A new meta-analysis found that continuous theta burst stimulation (cTBS), a novel form of brain stimulation therapy, does not appear to be more effective than sham (placebo) stimulation for treating symptoms of major depression. Key Facts: cTBS is a type of repetitive transcranial magnetic brain stimulation that aims to modulate activity in certain brain regions …

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Evaluating At-Home TDCS for Depression (HomeDC Trial)

An innovative study aims to assess the feasibility of patients self-managing transcranial direct current stimulation (tDCS) therapy for depression at home. This digitally-supported model could greatly expand access if proven safe, reliable and effective. Key Facts: tDCS uses scalp electrodes to deliver targeted electrical currents modulating brain activity Applied to prefrontal cortex, tDCS can have …

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