TL;DR: A 2026 review in Annals of Medicine argues that circadian rhythm disruption in major depressive disorder (MDD) reaches beyond poor sleep, linking clock-gene variation, sleep-wake timing, stress-hormone rhythms, melatonin signaling, and chronotherapy targets. Key Findings 264 million affected: The review frames MDD as a leading global disability cause affecting more than 264 million people. …
TL;DR: A 2026 systematic review and Bayesian meta-analysis in Journal of Medical Internet Research found that artificial intelligence models trained only on overnight pulse-oximetry oxygen-saturation data detected obstructive sleep apnea with 91.1% sensitivity and 88.4% specificity across 25 studies. Key Findings 25 studies and 23,171 participants were included: The review pooled adult studies that compared …
TL;DR: A 2026 study in Journal of Clinical Sleep Medicine found that after 12 months of watchful waiting for mild pediatric sleep-disordered breathing, only 13% of children progressed on polysomnography (PSG), an overnight sleep study, but 57% had persistent or worsening caregiver-reported symptoms. Key Findings 234 observed children: The analysis used the watchful-waiting arm of …
TL;DR: A 2026 meta-analysis in PLOS One found clinically important sleep problems in refugee and asylum-seeking populations, with pooled sleep-adversity prevalence of 43.2% in adults and 36.4% in children and adolescents. Key Findings 66 studies reviewed: The systematic review and meta-analysis covered 42,956 refugees and asylum seekers. 43.2% adult prevalence: Pooled sleep-adversity prevalence in adults …
TL;DR: A 2026 preprint in medRxiv found that poor sleep tracked faster biological aging across more than 64,000 adults, but twin and genetic analyses left the causal claim mixed rather than settled. Key Findings 64,000+ adults: Researchers tested sleep and aging biomarkers across five independent datasets spanning young, middle, and late adulthood. Poorer sleep quality: …
TL;DR: A 2026 randomized trial in BMC Anesthesiology found that adding an esketamine-adjuvanted stellate ganglion block to intraoperative esketamine plus dexmedetomidine reduced early postoperative sleep disturbance after gynecological laparoscopic surgery. Key Findings Sleep disturbance fell on day 1: Postoperative sleep disturbance affected 62.9% of patients in the stellate ganglion block group versus 83.2% in controls. …
TL;DR: A 2026 study protocol in PLOS One describes a planned longitudinal study that will track academic stress, depressive symptoms, diet, sleep-related wearable measures, salivary cortisol, and other health indicators across a university semester, but it does not yet report outcome results. Key Findings Study protocol only: The source describes the planned design and hypotheses; …
TL;DR: A 2026 cross-sectional study in PLOS One found that people with post COVID-19 condition reported worse quality of life, fatigue, sleep, psychological wellbeing, and subjective cognition than COVID-19 survivors without the condition, while many objective lung, metabolic, and cognitive tests did not differ. Key Findings 139-person Dutch cohort: The study included 87 people with …
TL;DR: A 2026 study in Psychological Medicine found that sleep quality partly explained how early adolescent depression, anxiety, and psychotic-like experience distress were linked to later school grades and social problems in the Adolescent Brain Cognitive Development Study. Key Findings Scale: Researchers analyzed 6,754 adolescents with grade data and 7,550 adolescents with social-problems data across …
TL;DR: A 2026 preprint on medRxiv found that in-person cognitive behavioral therapy for insomnia and several shorter behavioral versions were linked with higher post-treatment insomnia remission than sleep hygiene or other control conditions, but the evidence was strongest for full CBT-I. Key Findings 77 randomized trials: The network meta-analysis included 77 RCTs with 5,731 adults …
