Adult ADHD Linked to Lower SIRT-1, Nrf-2, and HO-1 Biomarkers

Adult ADHD Linked to Lower SIRT-1, Nrf-2, and HO-1 Biomarkers

TL;DR: A 2026 cross-sectional study in Metabolic Brain Disease linked adult attention-deficit/hyperactivity disorder (ADHD) with lower serum SIRT-1, Nrf-2, and HO-1, three redox-regulation markers tied to antioxidant defense. Key Findings 120 adults studied: The analysis compared 60 adults with ADHD against 60 age- and sex-matched healthy controls. SIRT-1 was lower: Mean serum SIRT-1 was 9.36 …

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Fidgeting May Enhance Attention in Adults with ADHD During Cognitively Demanding Tasks (2024 Study)

Fidgeting in adults with ADHD may serve as a compensatory mechanism to sustain attention during cognitively demanding tasks, particularly during correct task performance and when reaction time variability is low. Highlights: Fidgeting was significantly higher during correct trials compared to incorrect trials, suggesting it may aid in task performance. Increased fidgeting was observed in later …

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Solriamfetol for ADHD in Adults: Norepinephrine-Dopamine Reuptake Inhibitor

Attention-deficit/hyperactivity disorder (ADHD), long thought of as a childhood condition, is increasingly recognized as a disorder that can persist into adulthood. Up to 60% of children with ADHD continue to experience symptoms as adults. Yet treatment options specifically tested and approved for adult ADHD remain limited. A new study published this month in the Journal …

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