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Drugs & MedicationsJuly 2, 2026

HIV gp120 Strengthened Spinal NMDA Pain Signaling

TL;DR: A 2026 mouse study in The Journal of Neuroscience found that the HIV-1 protein gp120 amplified pain signaling through α2δ-1-bound NMDA receptors in spinal excitatory neurons, and blocking that receptor coupling reversed pain-like hypersensitivity. Key F…

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Drugs & MedicationsMay 8, 2026

Gabapentin Plus Hegu Embedding Improved Post-Herpetic Neuralgia

Gabapentin Plus Hegu Embedding Improved Post-Herpetic Neuralgia TL;DR: Adding weekly Hegu-point catgut embedding to gabapentin cut post-herpetic neuralgia pain and sleep disruption more sharply, raising response from 80.0% to 92.4%. Key Findings 210 randomized…

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HIV gp120 Strengthened Spinal NMDA Pain Signaling

Gabapentin Plus Hegu Embedding Improved Post-Herpetic Neuralgia

The findings. The context. The caveats.