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GLP-1 receptor agonists like semaglutide, used for managing Type 2 diabetes, may be linked to adverse mood changes, necessitating further investigation into their psychiatric effects. Highlights: GLP-1 Receptor Agonists: These medications mimic GLP-1 hormone e…
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TLDR: GLP-1 agonists were found to significantly reduce the risk of dementia in older individuals with type 2 diabetes mellitus (T2DM) compared to DPP-4 inhibitors and sulfonylureas. Highlights: A sequential trial emulation was conducted using data from Swedis…
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Semaglutide is emerging as a wonder drug for management of various metabolic diseases. Originally approved for type 2 diabetes, this glucagon like peptide-1 (GLP-1) receptor agonist is now showing promise for treating obesity, non-alcoholic steatohepatitis (NA…
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The FDA-approved diabetes drug semaglutide reduces alcohol drinking in mice and rats, suggesting it could be repurposed as an effective medication for alcohol use disorder (AUD). Key findings include: Semaglutide dose-dependently decreased binge-like drinking…
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