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Journal of Neuroinflammation

AlzheimersJuly 19, 2026

Microglial Checkpoint Collapse Mapped Alzheimer Neuroimmune Therapy Axes

TL;DR: A 2026 review in Journal of Neuroinflammation proposed that Alzheimer microglial dysfunction can be understood as checkpoint collapse, where failed regulatory controls feed three interacting lipid, iron/ferroptosis, and inflammation/complement axes. Key…

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MedicalJuly 2, 2026

Multiple Sclerosis Immunoglobulin Repertoires Shifted With Treatment

TL;DR: A 2026 study in Journal of Neuroinflammation found that people with multiple sclerosis had altered peripheral immunoglobulin repertoires, and several disease-modifying treatments shifted B-cell repertoire patterns after 6 months. Key Findings 33 MS pati…

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Microglial Checkpoint Collapse Mapped Alzheimer Neuroimmune Therapy Axes

Multiple Sclerosis Immunoglobulin Repertoires Shifted With Treatment

The findings. The context. The caveats.