Early Clozapine in Schizophrenia Linked to Lower Relapse Risk
TL;DR: A 2026 review in Current Opinion in Psychiatry found that earlier clozapine use in schizophrenia, especially after early nonresponse or relapse, was linked to better relapse prevention and stronger response rates than repeated nonclozapine antipsychotic trials. Key Findings Relapse prevention improved: Switching to clozapine after first relapse was associated with a 34% lower subsequent …
