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Synaptic Transmission

CognitionJune 28, 2026

Kainate Receptor Structures Showed How Partial Occupancy Avoided Desensitization

TL;DR: A 2026 study in Nature Communications used cryo-electron microscopy and patch-clamp recordings to show how partially occupied GluK2/GluK5 kainate receptors can activate without entering the fast desensitized state that normally shuts glutamate receptors…

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ConsciousnessSeptember 2, 2023

Rat Brains on Psychedelics: Hyper-Connectivity Between Regions

Researchers find similarities in brain activity induced by different psychedelic drugs in rats, providing clues to how they alter consciousness. Key facts: Psychedelic drugs like LSD and ketamine induce high-frequency brain waves that synchronize activity acro…

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Kainate Receptor Structures Showed How Partial Occupancy Avoided Desensitization

Rat Brains on Psychedelics: Hyper-Connectivity Between Regions

The findings. The context. The caveats.