TRD Brain Networks Decoupled Structure From Function
TL;DR: A 2026 study in npj Mental Health Research found that a 308-person multimodal MRI study found treatment-resistant depression carried a distinct structure-function decoupling pattern, and machine-learning models separated TRD from non-resistant depression with AUCs up to 0.95. Key Findings 72 TRD patients analyzed: The final sample included 72 patients with treatment-resistant depression, 152 with …
