Gut Microbiome and Depression in Children: How Missing Amino Acids May Drive the Connection
TL;DR: Dysbiotic bacteria in depressed adolescents cannot synthesize lysine and tryptophan, starving the brain of amino acids needed for glutamate transport and serotonin production—a causative link proven by transplanting dysbiotic bacteria into healthy rats. Depression in adolescents has tripled in the past two decades. Most treatments target a single neurotransmitter—serotonin. But a landmark multi-omics study …
