
Deep brain stimulation (DBS) is an emerging experimental therapy that has shown promise in treating patients with severe, treatment-resistant depression (TRD). Early research indicates DBS may help patients who have failed to respond to medications, psychother…
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A new study provides evidence that the psychedelic compound psilocybin has both immediate and lasting anti-inflammatory effects in healthy volunteers. The findings shed light on how psilocybin may improve mood, social behavior, and potentially treat depression…
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Research provides new evidence that generalized anxiety disorder (GAD) and depressive disorder (DD) have distinct patterns of brain activity. Machine learning analysis of EEG data reveals signature brain features that may enable more accurate diagnosis. Key Fa…
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New research suggests we may one day be able to vaccinate against depression, reducing suffering. Key facts: Depression is linked to inflammation in the body and brain. Anti-inflammatory treatments improve depression. Environmental factors like lack of contact…
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Depression and cognitive deficits are common health issues that impact millions of people. Scientists are testing a new drug, NSI-189, to see if it can help treat depression and improve thinking ability. Early research shows promise that NSI-189 may be able to…
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Depression is one of the most common and burdensome mental health disorders globally, affecting over 300 million people. While antidepressant medications can help many patients recover, up to a third do not respond adequately to first-line treatments. This has…
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Finasteride is a common medication used to treat hair loss and enlargement of the prostate gland. However, new research shows this drug may also increase the risk of depression and suicidal thoughts. Key Facts: Finasteride works by reducing levels of a hormone…
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A new study shows that delivering brain stimulation with mild electric current to the forehead at home could be an effective treatment option for people with depression. Key facts: The study tested at-home transcranial direct current stimulation (tDCS) in 16 p…
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Researchers have discovered that changes in a region deep in the brain called the brainstem may contribute to recurring major depressive disorder (MDD). Key findings include: Patients with first-episode and recurrent depression showed volume decreases in brain…
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Depression affects over 270 million people worldwide. New research is investigating whether manipulating gut bacteria with probiotics, prebiotics or synbiotics can help treat depression symptoms. Key Facts: Probiotics are live microorganisms that provide healt…
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