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Gut microbiota may influence epilepsy, but the exact mechanisms and involved microbiota are unclear, with potential treatments including ketogenic diets, probiotics, and fecal microbiota transplants being explored. Highlights: Approximately 33% of epilepsy pat…
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Researchers reviewed the potential impacts of physical exercise on the glymphatic system and its implications for neurodegenerative diseases, focusing on the mechanisms involved and the interplay between exercise and sleep quality. Highlights: The glymphatic s…
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Nanoparticle-enhanced radiotherapy (NERT) is a promising approach to improving brain tumor treatment by enhancing radiotherapy efficacy through targeted delivery and radiosensitization while overcoming challenges posed by the blood-brain barrier. Highlights: M…
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Cocaine Use Disorder (CUD) patients exhibit widespread gray matter atrophy, with specific brain volume deficits associated with crack-cocaine use and relapse outcomes. Highlights: Widespread Gray Matter Atrophy: CUD patients show significant gray matter volume…
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The study found that patients with social anxiety disorder (SAD) exhibit distinct structural brain alterations, including cortical thickening and thinning in specific regions, which fit into existing neurocircuitry models of the disorder. Highlights: Cortical…
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Antidepressant treatment in OCD is linked to structural and functional brain changes, particularly in corticosubcortical areas, but these findings need further validation in larger, more homogeneous samples. Highlights: Antidepressant Use: Antidepressants, esp…
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Fidgeting in adults with ADHD may serve as a compensatory mechanism to sustain attention during cognitively demanding tasks, particularly during correct task performance and when reaction time variability is low. Highlights: Fidgeting was significantly higher…
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A study found shared brain-specific mechanisms between Alzheimer’s disease (AD) and depression, particularly involving synaptic signaling and immune system pathways in the hippocampus, but no direct genetic overlap. Highlights: Six brain-specific eQTL genes (S…
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Lithium shows promise in treating traumatic brain injury (TBI) by mitigating neuroinflammation, protecting against neuronal damage, and improving cognitive functions. Highlights: Neuroprotective Mechanisms: Lithium’s therapeutic effects involve complex molecul…
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A study found a strong link between mitochondrial disorders and conditions like autism, ADHD, and various psychiatric issues. Highlights: Common Link: Mitochondrial disorders are frequently found in people with autism, ADHD, and intellectual disabilities. ASD…
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