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New research reveals that people with a history of methamphetamine dependence face a startling elevated risk of developing Parkinson’s disease or related movement disorders later in life. Key Facts: Individuals dependent on methamphetamine had almost 3 times t…
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A large review of research found that talk therapy works about as well as antidepressant medications for treating depression. The study also looked at other non-drug options, like exercise. While benefits were similar across treatments, side effects differed.…
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The NLRP3 inflammasome is increasingly being recognized as a mediator between inflammation and depression. Targeting this molecular complex shows promise for developing new antidepressant therapies. Key Facts: The NLRP3 inflammasome is made up of NLRP3, ASC, a…
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The naturally occurring peptide BPC 157 shows potential to treat stroke, schizophrenia symptoms, and spinal cord injury in animal models. Key facts: BPC 157 rapidly counteracted stroke damage and led to full recovery of memory, coordination and movement in rat…
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People struggling with substance use disorders often have difficulties with memory, attention, planning, and decision-making. New research explores how these cognitive deficits relate to treatment outcomes and whether targeting them could improve addiction rec…
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Researchers uncover a surprising molecular mechanism that explains ketamine’s exceptionally long-lasting antidepressant effects. Key Facts: Ketamine’s antidepressant effects last for days after its concentration drops to low, ineffective levels only an hour af…
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Depression is one of the most common mental health issues, affecting over 320 million people globally. Research shows that exercise may be an effective treatment option for many battling this disabling condition. Key Facts: Exercise has comparable antidepressa…
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Researchers conducted a comprehensive analysis comparing 20 antidepressants to identify the most effective options for preventing relapse in patients with major depressive disorder (MDD). Their findings suggest desvenlafaxine, paroxetine, venlafaxine and vorti…
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Major depressive disorder (MDD) is a global health crisis affecting over 300 million people. While available antidepressants help some patients, treatment is far from satisfactory for many. Exciting research into rapid-acting agents like ketamine and psilocybi…
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New research finds that regular running is just as effective as antidepressants for treating depression and anxiety, and leads to better physical health outcomes. Key Facts: In a study of 141 patients, running therapy and antidepressant medication had comparab…
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