alcohol use

COPE-A Reduced Youth PTSD Symptoms, But Substance Use Did Not Drop More Than Counseling

by
COPE-A Reduced Youth PTSD Symptoms, But Substance Use Did Not Drop More Than Counseling

TL;DR: A 2026 randomized trial analysis in European Journal of Psychotraumatology found that COPE-A, an integrated exposure-based therapy for youth with posttraumatic stress disorder (PTSD) and substance use disorder (SUD), reduced PTSD symptoms more than supportive counseling, but substance-use reductions were not significantly stronger than counseling. Key Findings 49 treated participants were analyzed: Youth aged …

Read more

South African Adolescent Substance Use Was High in 30-Study Meta-Analysis

by
South African Adolescent Substance Use Was High in 30-Study Meta-Analysis

TL;DR: A 2026 systematic review and meta-analysis in Drug and Alcohol Review estimated high adolescent substance-use exposure in South Africa, with lifetime alcohol use at 35.09%, tobacco at 25.47%, and cannabis at 10.47% across community and school-based studies. Key Findings 30 publications were included: Researchers synthesized 202 prevalence estimates from South African adolescent samples. Total …

Read more

Inflammation Markers Did Not Track Depression or Alcohol Use

by
Inflammation Markers Did Not Track Depression or Alcohol Use

TL;DR: A 2026 study in Brain, Behavior, & Immunity – Health found that depression symptoms, alcohol use, and alcohol use disorder (AUD) symptoms were not associated with C-reactive protein (CRP), a blood inflammation marker, or a pro-inflammatory cytokine index in 972 community adults, and twin analyses suggested familial confounding explained several cytokine-AUD links. Key Findings …

Read more

Brain Reward System Dysfunction in Depression & Mental Disorders

by

Researchers explored how our brain’s reward system connects to depression and other common mental health problems like social anxiety and eating disorders. They found that a dampened reward response seems to follow, rather than precede, symptoms of depression and other disorders. This highlights the important role that blunted enjoyment plays in the persistence of mental …

Read more