Why Depressed Brains Burn More ATP: The Cellular Energy Paradox of Fatigue
TL;DR: Young adults with depression produce ATP—the cell’s energy currency—at faster rates in both brain and blood, yet still feel more fatigued. New research reveals this is a compensatory mechanism that works at rest but collapses under stress, opening a fresh window into the biology of depression-related fatigue. Fatigue in major depression is relentless and …
