TL;DR: A 2026 study in PNAS from Oregon Health & Science University and Anhui University used optogenetics in mice to map a specific serotonin-producing brain circuit that runs straight to the auditory system, showed that activating this circuit produced tinnitus-like behavior, and traced a likely mechanism for why some patients on SSRI antidepressants report worsened …
TL;DR: A 2026 scoping review in Sleep Science linked seasonal timing, daylight exposure, daylight saving time (DST), sleep-wake rhythm disruption, and driver drowsiness to traffic-crash risk, but found that few studies directly integrate seasonality with chronobiology in one model. Key Findings 1,758 records screened: The scoping review used PRISMA-ScR methods and screened 1,758 records before …
TL;DR: A 2026 population-based matched cohort study in British Journal of Psychiatry found that risperidone use was associated with increased stroke risk, adjusted hazard ratio 1.28, while absolute stroke incidence was especially high in people with prior stroke or cardiovascular disease. Key Findings Matched dementia comparison: The analysis compared stroke risk among risperidone users and …
TL;DR: A 2026 randomized pilot trial in European Journal of Psychotraumatology found no overall PTSD advantage when refugee-focused emotion-regulation skills training was added before narrative exposure therapy, but refugees living with high visa or family insecurity showed preliminary self-report gains from the skills-first approach. Key Findings 71 adult refugees were randomized: Participants met DSM-5 criteria …
TL;DR: A 2026 birth cohort study in Environment & Health linked low-level prenatal lead exposure to lower infant Ages and Stages Questionnaire (ASQ-3) developmental scores, with FAM50B/PTCHD3 DNA methylation markers explaining part of the association. Key Findings Lead was the clearest metal finding: Among 21 detectable cord-blood metals, lead showed a consistent negative association with …
TL;DR: A 2026 European Journal of Pediatrics study found that children with phenylketonuria, or PKU, had higher depression scores and lower quality of life than controls, with the worse pattern in children diagnosed later. Key Findings Children studied: The study included 76 children ages 8-15, split into early-diagnosed PKU, late-diagnosed PKU, and healthy control groups. …
TL;DR: A 2026 Neurological Sciences study followed 216 early Parkinson’s patients for 2 years after levodopa started and found that several non-motor symptom differences between men and women persisted or emerged despite adjustment for baseline scores and levodopa dose. Key Findings 216 early Parkinson’s patients completed 24-month follow-up after starting levodopa, including 139 men and …
TL;DR: A 2026 mouse study in Communications Biology found that activating parvalbumin (PV) interneurons, inhibitory nerve cells in the orbitofrontal cortex, reduced default mode network connectivity and decreased normal social approach and sniffing behavior. Key Findings PV interneurons were targeted: Researchers used PV-Cre mice and a chemogenetic DREADD receptor to activate inhibitory PV interneurons in …
TL;DR: A 2026 retrospective ICU study in the International Journal of General Medicine found that 24-hour open visiting was associated with lower delirium incidence and lower anxiety/depression scores than 1-hour restricted visiting in chronic critically ill patients. Key Findings 264 ICU patients: The retrospective cohort included 132 restricted-visiting patients and 132 open-visiting patients. 24-hour access: …
TL;DR: A 2026 iScience study found that after 1 hour of training, adults could use a new audio cue for depth judgments, but only about half combined it with a familiar visual cue well enough to improve perceptual precision. Key Findings A total of 78 adults completed the depth task after training on an artificial …
