EXPLORE THE SCIENCE
A new meta-analysis found that continuous theta burst stimulation (cTBS), a novel form of brain stimulation therapy, does not appear to be more effective than sham (placebo) stimulation for treating symptoms of major depression. Key Facts: cTBS is a type of re…
Read article
Eating foods rich in certain flavonoids may help lower the risk of experiencing depressive symptoms, suggests new research based on U.S. national health data. Key facts: Higher intakes of anthocyanidins, flavanones, flavones, and isoflavones were associated wi…
Read article
An innovative study aims to assess the feasibility of patients self-managing transcranial direct current stimulation (tDCS) therapy for depression at home. This digitally-supported model could greatly expand access if proven safe, reliable and effective. Key F…
Read article
Recent research suggests that adjusting overall diet, rather than taking supplements, may help improve symptoms of depression. Whole food and whole diet interventions show promise as adjunctive treatments for depression, though more research is still needed. K…
Read article
A new study published in Frontiers in Psychiatry provides promising evidence that focused ultrasound stimulation of the prefrontal cortex can alleviate depressive behaviors in mice by suppressing inflammatory responses. Key facts: Researchers stimulated the pr…
Read article
Big picture: Psychoplastogens are a groundbreaking new class of psychoactive compounds that rapidly induce structural and functional changes in the brain, allowing pathological neural circuits to be rewired for therapeutic benefit. Key facts about psychoplasto…
Read article
New research demonstrates that repeated focused ultrasound treatments can have antidepressant-like effects in rats. The non-invasive technique was able to improve performance on a common test of depressive behaviors. While not a silver bullet solution, focused…
Read article
Fecal microbiota transplantation (FMT) shows potential as an effective new treatment for major depressive disorder (MDD). Key facts: FMT aims to restore a healthy gut microbiome which is thought to impact mood and mental health. Studies show links between gut…
Read article
Major depressive disorder (MDD) is a highly prevalent and debilitating condition. Novel treatment approaches are needed, especially for individuals with treatment-resistant depression. This study investigated the effects of adjunctive minocycline on immune-inf…
Read article
Depression and cognitive deficits are common health issues that impact millions of people. Scientists are testing a new drug, NSI-189, to see if it can help treat depression and improve thinking ability. Early research shows promise that NSI-189 may be able to…
Read article