
TL;DR: In sleeping mice, blood volume in the brain rose sharply during REM sleep, yet the energy molecule ATP inside neurons dropped. It bounced back as soon as the mice woke, suggesting REM sleep spends energy faster than blood supply alone can explain. Key F…
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The Energy Paradox: Why Depressed Brains Burn Faster TL;DR: Young adults with depression produce ATP—the cell’s energy currency—at faster rates in both brain and blood, yet still feel more fatigued. New research reveals this is a compensatory mechanism that wo…
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A new Mayo Clinic study is the first to clinically investigate whether antidepressants that impact mitochondrial function differently are associated with varying rates of treatment-emergent mania in bipolar disorder. The study found that antidepressants that i…
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