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TL;DR: Ambroxol, an old cough medicine, can boost a key brain enzyme in lab studies, but a review of 20 clinical reports found no proven benefit in Gaucher disease or GBA1-linked Parkinson’s. In a randomized trial of people with GBA1-linked Parkinson’s, ambrox…
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Gut Microbiome Signal Appeared Before Parkinson’s Symptoms in GBA1 Carriers TL;DR: In people carrying a genetic risk factor for Parkinson’s but not yet symptomatic, about 25% of their gut microbiome signature already looked intermediate between healthy control…
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Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopamine-producing neurons. Dopamine plays an important role in PD development. Here are some key facts: Dopamine is a chemical messenger in the brain involved in movement, m…
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