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A new study published in Frontiers in Psychiatry provides promising evidence that focused ultrasound stimulation of the prefrontal cortex can alleviate depressive behaviors in mice by suppressing inflammatory responses. Key facts: Researchers stimulated the pr…
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New research demonstrates that repeated focused ultrasound treatments can have antidepressant-like effects in rats. The non-invasive technique was able to improve performance on a common test of depressive behaviors. While not a silver bullet solution, focused…
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Fecal microbiota transplantation (FMT) shows potential as an effective new treatment for major depressive disorder (MDD). Key facts: FMT aims to restore a healthy gut microbiome which is thought to impact mood and mental health. Studies show links between gut…
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A new case-control study reveals an association between obesity, depression, and decreased levels of the protein neuregulin-1 (NRG-1). The research suggests NRG-1 may serve as a biomarker linking depression and obesity. Key facts: Depressive symptoms were more…
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Suicide is a leading cause of death globally, and people who use drugs are at heightened risk. Key facts: People who use opioids have 7-22 times the risk of suicide compared to the general population. Men who use drugs die by suicide more often, but women who…
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Major depressive disorder (MDD) is one of the most prevalent mental health conditions worldwide, yet its complex neurobiological underpinnings remain poorly understood. Emerging research implicates disturbances in neuronal apoptosis and neuroplasticity in the…
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A new study suggests higher levels of remnant cholesterol may increase the risk of depression. Remnant cholesterol is a type of lipoprotein that contains triglycerides and cholesterol and has been linked to atherosclerosis and cardiovascular disease. This larg…
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Major depressive disorder (MDD) is a highly prevalent and debilitating condition. Novel treatment approaches are needed, especially for individuals with treatment-resistant depression. This study investigated the effects of adjunctive minocycline on immune-inf…
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Suicide is a devastating public health problem, claiming hundreds of thousands of lives worldwide each year. Understanding the underlying biological and psychological factors that increase suicide risk is key for developing effective prevention and interventio…
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Depression affects over 120 million people worldwide, carrying a heavy burden of disability, mortality, and cost. While medications like SSRIs have provided relief for many, most patients fail to achieve full remission. After 30 years with few advances in phar…
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