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amitriptyline

CognitionJune 15, 2026

Amitriptyline Pollution Disrupted Male Guppy Spatial Learning

TL;DR: A 2026 study in Environmental Science & Technology found that male guppies exposed for 11 days to environmentally relevant amitriptyline, a tricyclic antidepressant detected in waterways, made more spatial-learning errors in a maze while females were la…

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Drugs & MedicationsMay 21, 2026

Amitriptyline Reduced C6 Glioma Cell Growth but Weakened Radiation Effects With Temozolomide

TL;DR: A 2026 in vitro study in Molecular and Clinical Oncology found that amitriptyline reduced C6 glioma cell viability and PD-L1 checkpoint expression, but the same drug weakened the cell-killing effect of radiation when combined with temozolomide. Key Find…

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Amitriptyline Pollution Disrupted Male Guppy Spatial Learning

Amitriptyline Reduced C6 Glioma Cell Growth but Weakened Radiation Effects With Temozolomide

The findings. The context. The caveats.