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Researchers conducted a comprehensive analysis comparing 20 antidepressants to identify the most effective options for preventing relapse in patients with major depressive disorder (MDD). Their findings suggest desvenlafaxine, paroxetine, venlafaxine and vorti…
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Antidepressant medications like bupropion (Zyban) show potential to help people quit smoking long-term. However, the evidence is complex with both benefits and risks to consider carefully. Key facts: The antidepressant bupropion (brand name Zyban) aids quittin…
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Major depressive disorder (MDD) is a global health crisis affecting over 300 million people. While available antidepressants help some patients, treatment is far from satisfactory for many. Exciting research into rapid-acting agents like ketamine and psilocybi…
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Antidepressants could potentially be repurposed as anticancer agents based on emerging evidence showing they can modulate autophagy—a process cancer cells rely on for growth and survival. Key Facts: Many antidepressants like SSRIs and TCAs have demonstrated an…
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New research finds that regular running is just as effective as antidepressants for treating depression and anxiety, and leads to better physical health outcomes. Key Facts: In a study of 141 patients, running therapy and antidepressant medication had comparab…
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Depression affects over 300 million people globally. Current antidepressants have limited efficacy and slow onset of action. New research shows promise for compounds targeting metabotropic glutamate receptors 2 and 3 (mGluR2/3) as fast-acting antidepressants w…
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The European Medicines Agency (EMA) has updated its guidance on clinical trials for new depression treatments, with the goals of harmonizing standards across the EU and facilitating development of improved therapies. Key Facts: Depression is a highly disabling…
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Medications are meant to treat medical conditions and improve health, but some can have the unintended consequence of weight gain, which can then worsen other health risks. Understanding which medications tend to cause weight gain and the mechanisms behind thi…
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Depression is a major global health issue, but diet may be an effective yet overlooked treatment approach. New research identifies the top food sources of 12 key nutrients that help prevent and treat depression. Oysters, organ meats, leafy greens, lettuces, pe…
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A new study published in Pharmazie takes a close look at adverse event reports related to drug-induced weight gain submitted to the FDA over the past 10 years. The retrospective analysis provides insight into the drugs most commonly associated with weight gain…
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